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Proteolysis of α-Synuclein Fibrils in the Lysosomal Pathway Limits Induction of Inclusion Pathology
Progression of α-synuclein inclusion pathology may occur through cycles of release and uptake of α-synuclein aggregates, which induce additional intracellular α-synuclein inclusion pathology. This process may explain i) the presence of α-synuclein inclusion pathology in grafted cells in human brains...
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| Published in: | J Neurochem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452425/ https://ncbi.nlm.nih.gov/pubmed/27424880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13743 |
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