FKBP8 recruits LC3A to mediate Parkin‐independent mitophagy

Mitophagy, the selective removal of damaged or excess mitochondria by autophagy, is an important process in cellular homeostasis. The outer mitochondrial membrane (OMM) proteins NIX, BNIP3, FUNDC1, and Bcl2‐L13 recruit ATG8 proteins (LC3/GABARAP) to mitochondria during mitophagy. FKBP8 (also known a...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Bhujabal, Zambarlal, Birgisdottir, Åsa B, Sjøttem, Eva, Brenne, Hanne B, Øvervatn, Aud, Habisov, Sabrina, Kirkin, Vladimir, Lamark, Trond, Johansen, Terje
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452039/
https://ncbi.nlm.nih.gov/pubmed/28381481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643147
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