FKBP8 recruits LC3A to mediate Parkin‐independent mitophagy

Mitophagy, the selective removal of damaged or excess mitochondria by autophagy, is an important process in cellular homeostasis. The outer mitochondrial membrane (OMM) proteins NIX, BNIP3, FUNDC1, and Bcl2‐L13 recruit ATG8 proteins (LC3/GABARAP) to mitochondria during mitophagy. FKBP8 (also known a...

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發表在:EMBO Rep
Main Authors: Bhujabal, Zambarlal, Birgisdottir, Åsa B, Sjøttem, Eva, Brenne, Hanne B, Øvervatn, Aud, Habisov, Sabrina, Kirkin, Vladimir, Lamark, Trond, Johansen, Terje
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452039/
https://ncbi.nlm.nih.gov/pubmed/28381481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643147
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