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PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing
Brown adipose has the potential to counteract obesity, and thus, identifying signaling pathways that regulate the activity of this tissue is of great clinical interest. PRDM16 is a transcription factor that activates brown fat‐specific genes while repressing white fat and muscle‐specific genes in ad...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452012/ https://ncbi.nlm.nih.gov/pubmed/28408438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695588 |
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