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PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing

Brown adipose has the potential to counteract obesity, and thus, identifying signaling pathways that regulate the activity of this tissue is of great clinical interest. PRDM16 is a transcription factor that activates brown fat‐specific genes while repressing white fat and muscle‐specific genes in ad...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Kissig, Megan, Ishibashi, Jeff, Harms, Matthew J, Lim, Hee‐Woong, Stine, Rachel R, Won, Kyoung‐Jae, Seale, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452012/
https://ncbi.nlm.nih.gov/pubmed/28408438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695588
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