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PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing

Brown adipose has the potential to counteract obesity, and thus, identifying signaling pathways that regulate the activity of this tissue is of great clinical interest. PRDM16 is a transcription factor that activates brown fat‐specific genes while repressing white fat and muscle‐specific genes in ad...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Kissig, Megan, Ishibashi, Jeff, Harms, Matthew J, Lim, Hee‐Woong, Stine, Rachel R, Won, Kyoung‐Jae, Seale, Patrick
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452012/
https://ncbi.nlm.nih.gov/pubmed/28408438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695588
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