PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program

PR (PRD1–BF1–RIZ1 homologous) domain-containing 16 (PRDM16) drives a brown fat differentiation program, but the mechanisms by which PRDM16 activates brown fat-selective genes have been unclear. Through chromatin immunoprecipitation (ChIP) followed by deep sequencing (ChIP-seq) analyses in brown adip...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Harms, Matthew J., Lim, Hee-Woong, Ho, Yugong, Shapira, Suzanne N., Ishibashi, Jeff, Rajakumari, Sona, Steger, David J., Lazar, Mitchell A., Won, Kyoung-Jae, Seale, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318146/
https://ncbi.nlm.nih.gov/pubmed/25644604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252734.114
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