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EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

The transcription factor early B-cell factor 2 (EBF2) is an essential mediator of brown adipocyte commitment and terminal differentiation. However, the mechanisms by which EBF2 regulates chromatin to activate brown fat-specific genes in adipocytes were unknown. ChIP-seq (chromatin immunoprecipitatio...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Shapira, Suzanne N., Lim, Hee-Woong, Rajakumari, Sona, Sakers, Alexander P., Ishibashi, Jeff, Harms, Matthew J., Won, Kyoung-Jae, Seale, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411707/
https://ncbi.nlm.nih.gov/pubmed/28428261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294405.116
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