Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

The white adipose organ is composed of both subcutaneous and several intra-abdominal depots. Excess abdominal adiposity is a major risk factor for metabolic disease in rodents and humans, while expansion of subcutaneous fat does not carry the same risks. Brown adipose produces heat as a defense agai...

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Главные авторы: Seale, Patrick, Conroe, Heather M., Estall, Jennifer, Kajimura, Shingo, Frontini, Andrea, Ishibashi, Jeff, Cohen, Paul, Cinti, Saverio, Spiegelman, Bruce M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2010
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007155/
https://ncbi.nlm.nih.gov/pubmed/21123942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44271
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