Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis

BACKGROUND. Cardiac dysfunction is present in >40% of sepsis patients and is associated with mortality rates of up to 70%. Recent evidence suggests that glycolytic metabolism plays a critical role in host defense and inflammation. Activation of Toll-like receptors on immune cells can enhance glyc...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Zheng, Zhibo, Ma, He, Zhang, Xia, Tu, Fei, Wang, Xiaohui, Ha, Tuanzhu, Fan, Min, Liu, Li, Xu, Jingjing, Yu, Kaijiang, Wang, Ruitao, Kalbfleisch, John, Kao, Race, Williams, David, Li, Chuanfu
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Major Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451607/
https://ncbi.nlm.nih.gov/pubmed/28368517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix138
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