The Toll-like Receptor 9 Ligand, CpG Oligodeoxynucleotide, Attenuates Cardiac Dysfunction in Polymicrobial Sepsis, Involving Activation of Both Phosphoinositide 3 Kinase/Akt and Extracellular-Signal-Related Kinase Signaling

Background. Toll-like receptors (TLRs) play a role in the pathophysiology of sepsis and multiple organ failure. This study examined the effect of CpG oligodeoxynucleotide (CpG-ODN), the TLR9 ligand, on polymicrobial sepsis–induced cardiac dysfunction. Methods. Male C57BL/6 mice were treated with CpG...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Ming, Ha, Tuanzhu, Zhang, Xia, Wang, Xiaohui, Liu, Li, Kalbfleisch, John, Singh, Krishna, Williams, David, Li, Chuanfu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693590/
https://ncbi.nlm.nih.gov/pubmed/23359590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit036
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados