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CpG-ODN, the TLR9 agonist, attenuates myocardial ischemia/reperfusion injury: involving activation of PI3K/Akt signaling

BACKGROUND: Toll-like receptors (TLRs) have been implicated in myocardial ischemia/reperfusion (I/R) injury. The TLR9 ligand, CpG-ODN has been reported to improve cell survival. We examined effect of CpG-ODN on myocardial I/R injury. METHODS: Male C57BL/6 mice were treated with either CpG-ODN, contr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cao, Zhijuan, Ren, Danyang, Ha, Tuanzhu, Liu, Li, Wang, Xiaohui, Kalbfleisch, John, Gao, Xiang, Kao, Race, Williams, David, Li, Chuanfu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518630/
https://ncbi.nlm.nih.gov/pubmed/22917564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.08.008
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