TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism

AIMS: Toll-like receptor (TLR)-mediated signalling pathways have been implicated in myocardial ischaemia/reperfusion (I/R) injury. Activation of the phosphoinositide 3-kinase (PI3K)/Akt pathway protects the myocardium from ischaemic injury. We hypothesized that the modulation of TLR2 would induce ca...

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Main Authors: Ha, Tuanzhu, Hu, Yulong, Liu, Li, Lu, Chen, McMullen, Julie R., Kelley, Jim, Kao, Race L., Williams, David L., Gao, Xiang, Li, Chuanfu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920812/
https://ncbi.nlm.nih.gov/pubmed/20421349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq116
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