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TLR2 ligand induces protection against cerebral ischemia/reperfusion injury: via activation of PI3K/Akt signaling
This study examined the effect of TLR2 activation by its specific ligand, Pam3CSK4, on cerebral ischemia/reperfusion (I/R) injury. Mice (n=8/group) were treated with Pam3CSK4 one hr before cerebral ischemia (60 min) followed by reperfusion (24 hrs). Pam3CSK4 was also given to the mice (n=8) 30 min a...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140609/ https://ncbi.nlm.nih.gov/pubmed/21709150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003428 |
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