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TLR2 ligand induces protection against cerebral ischemia/reperfusion injury: via activation of PI3K/Akt signaling

This study examined the effect of TLR2 activation by its specific ligand, Pam3CSK4, on cerebral ischemia/reperfusion (I/R) injury. Mice (n=8/group) were treated with Pam3CSK4 one hr before cerebral ischemia (60 min) followed by reperfusion (24 hrs). Pam3CSK4 was also given to the mice (n=8) 30 min a...

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Detalhes bibliográficos
Main Authors: Lu, Chen, Liu, Li, Chen, Yuling, Ha, Tuanzhu, Kelley, Jim, Schweitzer, John, Kalbfleisch, John H., Kao, Race L., Williams, David L., Li, Chuanfu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140609/
https://ncbi.nlm.nih.gov/pubmed/21709150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003428
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