Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner

Cystic fibrosis-related diabetes is the most common comorbidity associated with cystic fibrosis (CF) and correlates with increased rates of lung function decline. Because glucose is a nutrient present in the airways of patients with bacterial airway infections and because insulin controls glucose me...

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Bibliografske podrobnosti
izdano v:Am J Physiol Lung Cell Mol Physiol
Main Authors: Molina, Samuel A., Moriarty, Hannah K., Infield, Daniel T., Imhoff, Barry R., Vance, Rachel J., Kim, Agnes H., Hansen, Jason M., Hunt, William R., Koval, Michael, McCarty, Nael A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451595/
https://ncbi.nlm.nih.gov/pubmed/28213469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00364.2016
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