Junctional abnormalities in human airway epithelial cells expressing F508del CFTR

Cystic fibrosis (CF) has a profound impact on airway physiology. Accumulating evidence suggests that intercellular junctions are impaired in CF. We examined changes to CF transmembrane conductance regulator (CFTR) function, tight junctions, and gap junctions in NuLi-1 (CFTR(wt/wt)) and CuFi-5 (CFTR(...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Molina, Samuel A., Stauffer, Brandon, Moriarty, Hannah K., Kim, Agnes H., McCarty, Nael A., Koval, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556929/
https://ncbi.nlm.nih.gov/pubmed/26115671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00060.2015
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