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Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells

The functional expression of the epithelial sodium channel (ENaC) appears elevated in cystic fibrosis (CF) airway epithelia, but the mechanism by which this occurs is not clear. We tested the hypothesis that the cystic fibrosis transmembrane conductance regulator (CFTR) alters the trafficking of end...

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Autori principali: Rubenstein, Ronald C., Lockwood, Shannon R., Lide, Ellen, Bauer, Rebecca, Suaud, Laurence, Grumbach, Yael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023291/
https://ncbi.nlm.nih.gov/pubmed/20935229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00142.2010
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