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Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells

The functional expression of the epithelial sodium channel (ENaC) appears elevated in cystic fibrosis (CF) airway epithelia, but the mechanism by which this occurs is not clear. We tested the hypothesis that the cystic fibrosis transmembrane conductance regulator (CFTR) alters the trafficking of end...

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Библиографические подробности
Главные авторы: Rubenstein, Ronald C., Lockwood, Shannon R., Lide, Ellen, Bauer, Rebecca, Suaud, Laurence, Grumbach, Yael
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023291/
https://ncbi.nlm.nih.gov/pubmed/20935229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00142.2010
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