Junctional abnormalities in human airway epithelial cells expressing F508del CFTR

Cystic fibrosis (CF) has a profound impact on airway physiology. Accumulating evidence suggests that intercellular junctions are impaired in CF. We examined changes to CF transmembrane conductance regulator (CFTR) function, tight junctions, and gap junctions in NuLi-1 (CFTR(wt/wt)) and CuFi-5 (CFTR(...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Molina, Samuel A., Stauffer, Brandon, Moriarty, Hannah K., Kim, Agnes H., McCarty, Nael A., Koval, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556929/
https://ncbi.nlm.nih.gov/pubmed/26115671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00060.2015
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