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Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes

Microvascular dysfunction is considered an integral part of Alzheimer disease (AD) pathogenesis, but the possible relationship between amyloid pathology, microvascular dysfunction and cell death is still unclear. In order to investigate the influence of intraneuronal amyloid-β (Aβ) accumulation on v...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Baldassarro, Vito Antonio, Marchesini, Alessandra, Giardino, Luciana, Calzà, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451168/
https://ncbi.nlm.nih.gov/pubmed/28237964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028001
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