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Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes

Microvascular dysfunction is considered an integral part of Alzheimer disease (AD) pathogenesis, but the possible relationship between amyloid pathology, microvascular dysfunction and cell death is still unclear. In order to investigate the influence of intraneuronal amyloid-β (Aβ) accumulation on v...

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Podrobná bibliografie
Vydáno v:Dis Model Mech
Hlavní autoři: Baldassarro, Vito Antonio, Marchesini, Alessandra, Giardino, Luciana, Calzà, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451168/
https://ncbi.nlm.nih.gov/pubmed/28237964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028001
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