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Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes

Microvascular dysfunction is considered an integral part of Alzheimer disease (AD) pathogenesis, but the possible relationship between amyloid pathology, microvascular dysfunction and cell death is still unclear. In order to investigate the influence of intraneuronal amyloid-β (Aβ) accumulation on v...

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Publicat a:Dis Model Mech
Autors principals: Baldassarro, Vito Antonio, Marchesini, Alessandra, Giardino, Luciana, Calzà, Laura
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451168/
https://ncbi.nlm.nih.gov/pubmed/28237964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028001
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