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Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

The aberrant accumulation of aggregated β-amyloid peptides (Aβ) as plaques is a hallmark of Alzheimer’s disease (AD) neuropathology and reduction of Aβ has become a leading direction of emerging experimental therapies for the disease. The mechanism(s) whereby Aβ is involved in the pathophysiology of...

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Hlavní autoři: Gouras, Gunnar K., Tampellini, Davide, Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183823/
https://ncbi.nlm.nih.gov/pubmed/20354705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0679-9
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