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Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
The aberrant accumulation of aggregated β-amyloid peptides (Aβ) as plaques is a hallmark of Alzheimer’s disease (AD) neuropathology and reduction of Aβ has become a leading direction of emerging experimental therapies for the disease. The mechanism(s) whereby Aβ is involved in the pathophysiology of...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183823/ https://ncbi.nlm.nih.gov/pubmed/20354705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0679-9 |
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