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Co-occurrence of Alzheimer’s disease β-amyloid and tau pathologies at synapses

Although β-amyloid (Aβ) plaques and tau neurofibrillary tangles are hallmarks of Alzheimer’s disease (AD) neuropathology, loss of synapses is considered the best correlate of cognitive decline in AD, rather than plaques or tangles. How pathological Aβ and tau aggregation relate to each other and to...

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Detalhes bibliográficos
Main Authors: Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz, Lin, Michael T., Milner, Teresa A., Gouras, Gunnar K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909664/
https://ncbi.nlm.nih.gov/pubmed/18771816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.07.021
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