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Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain

Multiple lines of evidence implicate β-amyloid (Aβ) in the pathogenesis of Alzheimer's disease (AD), but the mechanisms whereby Aβ is involved remain unclear. Addition of Aβ to the extracellular space can be neurotoxic. Intraneuronal Aβ42 accumulation is also associated with neurodegeneration....

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書目詳細資料
發表在:J Neurosci
Main Authors: Takahashi, Reisuke H., Almeida, Claudia G., Kearney, Patrick F., Yu, Fangmin, Lin, Michael T., Milner, Teresa A., Gouras, Gunnar K.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729733/
https://ncbi.nlm.nih.gov/pubmed/15071107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5167-03.2004
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