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Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain

Multiple lines of evidence implicate β-amyloid (Aβ) in the pathogenesis of Alzheimer's disease (AD), but the mechanisms whereby Aβ is involved remain unclear. Addition of Aβ to the extracellular space can be neurotoxic. Intraneuronal Aβ42 accumulation is also associated with neurodegeneration....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Takahashi, Reisuke H., Almeida, Claudia G., Kearney, Patrick F., Yu, Fangmin, Lin, Michael T., Milner, Teresa A., Gouras, Gunnar K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729733/
https://ncbi.nlm.nih.gov/pubmed/15071107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5167-03.2004
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