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Impaired β-Amyloid Secretion in Alzheimer's Disease Pathogenesis
A central question in Alzheimer's disease (AD) research is what role β-amyloid peptide (Aβ) plays in synaptic dysfunction. Synaptic activity increases Aβ secretion, potentially inhibiting synapses, but also decreases intraneuronal Aβ, protecting synapses. We now show that levels of secreted Aβ...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Society for Neuroscience
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225957/ https://ncbi.nlm.nih.gov/pubmed/22031884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2986-11.2011 |
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