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Synapses, Synaptic Activity and Intraneuronal Aβ in Alzheimer's Disease

β-Amyloid peptide accumulation plays a central role in the pathogenesis of Alzheimer's disease. Aberrant β-amyloid buildup in the brain has been shown to be present both in the extracellular space and within neurons. Synapses are important targets of β-amyloid, and alterations in synapses bette...

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Hlavní autoři: Tampellini, Davide, Gouras, Gunnar K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912028/
https://ncbi.nlm.nih.gov/pubmed/20725518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00013
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