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Critical role of intraneuronal Aβ in Alzheimer’s disease: technical challenges in studying intracellular Aβ
AIMS: Multiple lines of evidence have implicated β-amyloid (Aβ) in the pathogenesis of Alzheimer’s disease (AD). However, the mechanism(s) whereby Aβ is involved in the disease process remains unclear. The dominant hypothesis in AD has been that Aβ initiates the disease via toxicity from secreted, e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479332/ https://ncbi.nlm.nih.gov/pubmed/22727791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.004 |
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