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Critical role of intraneuronal Aβ in Alzheimer’s disease: technical challenges in studying intracellular Aβ

AIMS: Multiple lines of evidence have implicated β-amyloid (Aβ) in the pathogenesis of Alzheimer’s disease (AD). However, the mechanism(s) whereby Aβ is involved in the disease process remains unclear. The dominant hypothesis in AD has been that Aβ initiates the disease via toxicity from secreted, e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gouras, Gunnar K., Willén, Katarina, Tampellini, Davide
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479332/
https://ncbi.nlm.nih.gov/pubmed/22727791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.004
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