Synaptic Activity Reduces Intraneuronal Aβ, Promotes APP Transport to Synapses, and Protects against Aβ-Related Synaptic Alterations

A central question in Alzheimer's disease research is what role synaptic activity plays in the disease process. Synaptic activity has been shown to induce β-amyloid peptide release into the extracellular space, and extracellular β-amyloid has been shown to be toxic to synapses. We now provide e...

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Hlavní autoři: Tampellini, Davide, Rahman, Nawreen, Gallo, Eduardo F., Huang, Zhenyong, Dumont, Magali, Capetillo-Zarate, Estibaliz, Ma, Tao, Zheng, Rong, Lu, Bao, Nanus, David M., Lin, Michael T., Gouras, Gunnar K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763626/
https://ncbi.nlm.nih.gov/pubmed/19657023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2292-09.2009
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