Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice

BACKGROUND: Alzheimer disease is a multifactorial disorder characterized by the progressive deterioration of neuronal networks. The pathological hallmarks includes extracellular amyloid plaques and intraneuronal neurofibrillary tangles, but the primary cause is only partially understood. Thus, there...

Full description

Saved in:
Bibliographic Details
Main Authors: Sivilia, Sandra, Lorenzini, Luca, Giuliani, Alessandro, Gusciglio, Marco, Fernandez, Mercedes, Baldassarro, Vito Antonio, Mangano, Chiara, Ferraro, Luca, Pietrini, Vladimiro, Baroc, Maria Francesca, Viscomi, Arturo R, Ottonello, Simone, Villetti, Gino, Imbimbo, Bruno P, Calzà, Laura, Giardino, Luciana
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626610/
https://ncbi.nlm.nih.gov/pubmed/23560952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-44
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items