Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery

AIM: To develop an in vitro model based on neural stem cells derived from transgenic animals, to be used in the study of pathological mechanisms of Alzheimer’s disease and for testing new molecules. METHODS: Neural stem cells (NSCs) were isolated from the subventricular zone of Wild type (Wt) and Tg...

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Detalhes bibliográficos
Main Authors: Baldassarro, Vito Antonio, Lizzo, Giulia, Paradisi, Michela, Fernández, Mercedes, Giardino, Luciana, Calzà, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2013
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Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812526/
https://ncbi.nlm.nih.gov/pubmed/24179610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v5.i4.229
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