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The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein
The biological function of α-Synuclein has been related to binding to lipids and membranes but these interactions can also mediate α-Synuclein aggregation, which is associated to Parkinson’s disease and other neuropathologies. In brain tissue α-Synuclein is constitutively N-acetylated, a modificatio...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451137/ https://ncbi.nlm.nih.gov/pubmed/28562630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178576 |
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