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Exploring the accessible conformations of N-terminal acetylated α-synuclein

Alpha synuclein (αsyn) fibrils are found in the Lewy Bodies of patients with Parkinson’s disease (PD). The aggregation of the αsyn monomer to soluble oligomers and insoluble fibril aggregates is believed to be one of the causes of PD. Recently, the view of the native state of αsyn as a monomeric ens...

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Detalhes bibliográficos
Main Authors: Moriarty, Gina M., Janowska, Maria K., Kang, Lijuan, Baum, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201235/
https://ncbi.nlm.nih.gov/pubmed/23499431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.02.049
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