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Exploring the accessible conformations of N-terminal acetylated α-synuclein

Alpha synuclein (αsyn) fibrils are found in the Lewy Bodies of patients with Parkinson’s disease (PD). The aggregation of the αsyn monomer to soluble oligomers and insoluble fibril aggregates is believed to be one of the causes of PD. Recently, the view of the native state of αsyn as a monomeric ens...

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Autori principali: Moriarty, Gina M., Janowska, Maria K., Kang, Lijuan, Baum, Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201235/
https://ncbi.nlm.nih.gov/pubmed/23499431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.02.049
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