Sequential EMT-MET induces neuronal conversion through Sox2

Direct neuronal conversion can be achieved with combinations of small-molecule compounds and growth factors. Here, by studying the first or induction phase of the neuronal conversion induced by defined 5C medium, we show that the Sox2-mediated switch from early epithelial–mesenchymal transition (EMT...

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Bibliografiske detaljer
Udgivet i:Cell Discov
Main Authors: He, Songwei, Chen, Jinlong, Zhang, Yixin, Zhang, Mengdan, Yang, Xiao, Li, Yuan, Sun, Hao, Lin, Lilong, Fan, Ke, Liang, Lining, Feng, Chengqian, Wang, Fuhui, Zhang, Xiao, Guo, Yiping, Pei, Duanqing, Zheng, Hui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450022/
https://ncbi.nlm.nih.gov/pubmed/28580167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2017.17
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