APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast

Variations in mutation rates across the genome have been demonstrated both in model organisms and in cancers. This phenomenon is largely driven by the damage specificity of diverse mutagens and the differences in DNA repair efficiency in given genomic contexts. Here, we demonstrate that the single-s...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Saini, Natalie, Roberts, Steven A., Sterling, Joan F., Malc, Ewa P., Mieczkowski, Piotr A., Gordenin, Dmitry A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450012/
https://ncbi.nlm.nih.gov/pubmed/28351647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.03.003
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