APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast

Variations in mutation rates across the genome have been demonstrated both in model organisms and in cancers. This phenomenon is largely driven by the damage specificity of diverse mutagens and the differences in DNA repair efficiency in given genomic contexts. Here, we demonstrate that the single-s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:DNA Repair (Amst)
Prif Awduron: Saini, Natalie, Roberts, Steven A., Sterling, Joan F., Malc, Ewa P., Mieczkowski, Piotr A., Gordenin, Dmitry A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450012/
https://ncbi.nlm.nih.gov/pubmed/28351647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.03.003
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