Chargement en cours...
APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication
APOBEC family cytidine deaminases have been recently implicated as powerful mutators of cancer genomes. How APOBECs, which are ssDNA specific enzymes, gain access to chromosomal DNA is unclear. To ascertain the chromosomal ssDNA substrates of the APOBECs, we expressed APOBEC3A and APOBEC3B, the two...
Enregistré dans:
| Publié dans: | Cell Rep |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4758883/ https://ncbi.nlm.nih.gov/pubmed/26832400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.021 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|