TDP-43 suppresses tau expression via promoting its mRNA instability

In the brains of individuals with Alzheimer's disease (AD) and chronic traumatic encephalopathy, tau pathology is accompanied usually by intracellular aggregation of transactive response DNA-binding protein 43 (TDP-43). However, the role of TDP-43 in tau pathogenesis is not understood. Here, we...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Gu, Jianlan, Wu, Feng, Xu, Wen, Shi, Jianhua, Hu, Wen, Jin, Nana, Qian, Wei, Wang, Xinglong, Iqbal, Khalid, Gong, Cheng-Xin, Liu, Fei
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449590/
https://ncbi.nlm.nih.gov/pubmed/28335005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx175
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