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Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A
Abnormal alternative splicing of tau exon 10 results in imbalance of 3R-tau and 4R-tau expression, which is sufficient to cause neurofibrillary degeneration. Splicing factor SC35, a member of the superfamily of the serine/arginine-rich (SR) proteins, promotes tau exon 10 inclusion. The molecular mec...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152345/ https://ncbi.nlm.nih.gov/pubmed/21470964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr195 |
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