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Splicing factor SC35 promotes tau expression through stabilization of its mRNA
Altered alternative splicing and accumulation of brain microtubule-associated protein tau are found in several tauopathies and are believed to lead to these neurodegenerative diseases. We found that in addition to promote tau exon 10 inclusion, splicing factor SC35 also promoted tau expression in HE...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071244/ https://ncbi.nlm.nih.gov/pubmed/21333649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.02.017 |
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