How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?

The human epidermal growth factor receptor 2 (HER2)/receptor tyrosine-protein kinasebB-2 (ERBB2) is overexpressed in 20–30% of breast tumors leading to faster growing and more aggressive tumors. Alternative splicing generates a functionally distinct HER2 variant called Herstatin, which is produced b...

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Vydáno v:RNA Biol
Hlavní autoři: Silipo, Marco, Gautrey, Hannah, Satam, Swapna, Lennard, Thomas, Tyson-Capper, Alison
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449083/
https://ncbi.nlm.nih.gov/pubmed/27935425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1267074
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