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HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

Overexpression of the HER2 receptor occurs in approximately 20% of breast cancer patients. HER2 positivity is associated with poor prognosis and aggressive tumour phenotypes, which led to rapid progress in HER2 targeted therapeutics and diagnostic testing. Whilst these advances have greatly increase...

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Publicat a:Oncotarget
Autors principals: Hart, Vic, Gautrey, Hannah, Kirby, John, Tyson-Capper, Alison
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679030/
https://ncbi.nlm.nih.gov/pubmed/33245725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27789
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