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HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

Overexpression of the HER2 receptor occurs in approximately 20% of breast cancer patients. HER2 positivity is associated with poor prognosis and aggressive tumour phenotypes, which led to rapid progress in HER2 targeted therapeutics and diagnostic testing. Whilst these advances have greatly increase...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hart, Vic, Gautrey, Hannah, Kirby, John, Tyson-Capper, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679030/
https://ncbi.nlm.nih.gov/pubmed/33245725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27789
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