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HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

Overexpression of the HER2 receptor occurs in approximately 20% of breast cancer patients. HER2 positivity is associated with poor prognosis and aggressive tumour phenotypes, which led to rapid progress in HER2 targeted therapeutics and diagnostic testing. Whilst these advances have greatly increase...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Hart, Vic, Gautrey, Hannah, Kirby, John, Tyson-Capper, Alison
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679030/
https://ncbi.nlm.nih.gov/pubmed/33245725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27789
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