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Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells

Myeloid cell leukemia-1 (Mcl −1) is one of the most frequently amplified genes in cancer, and its overexpression is associated with poor prognosis and drug resistance. As a member of the Bcl-2 family it is involved in the control of the mitochondrial (intrinsic) cell death pathway. Alternative splic...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Tyson-Capper, Alison, Gautrey, Hannah
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333436/
https://ncbi.nlm.nih.gov/pubmed/30468106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1551692
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