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Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance
Overexpression of human epidermal growth factor receptor (HER-2) occurs in 20–30% of breast cancers and confers survival and proliferative advantages on the tumour cells making HER-2 an ideal therapeutic target for drugs like Herceptin. Continued delineation of tumour biology has identified splice v...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713377/ https://ncbi.nlm.nih.gov/pubmed/23935627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/973584 |
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