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How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?
The human epidermal growth factor receptor 2 (HER2)/receptor tyrosine-protein kinasebB-2 (ERBB2) is overexpressed in 20–30% of breast tumors leading to faster growing and more aggressive tumors. Alternative splicing generates a functionally distinct HER2 variant called Herstatin, which is produced b...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449083/ https://ncbi.nlm.nih.gov/pubmed/27935425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1267074 |
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