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Selective Tissue Distribution Mediates Tissue-Dependent PPARγ Activation and Insulin Sensitization by INT131, a Selective PPARγ Modulator

The mechanisms underlying the enhancement of insulin sensitivity by selective peroxisome proliferator-activated receptor γ modulators (sPPARγMs) are still not completely known. Here, the representative sPPARγM, INT131, was used as a probe to investigate the insulin-sensitizing mechanisms of sPPARγM...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Xie, Xinni, Chen, Wei, Zhang, Ning, Yuan, Mei, Xu, Cheng, Zheng, Zhibing, Li, Hua, Wang, Lili
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447729/
https://ncbi.nlm.nih.gov/pubmed/28611668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00317
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