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The Development of INT131 as a Selective PPARγ Modulator: Approach to a Safer Insulin Sensitizer
INT131 (formerly T0903131, T131, AMG131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor γ modulator (SPPARM) currently in Phase 2 clinical trials for treatment of type-2 diabetes mellitus (T2DM). This new chemical entity represents a second generation SP...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2522386/ https://ncbi.nlm.nih.gov/pubmed/18769500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/936906 |
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