Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity

PPARγ activation in type 2 diabetic patients results in a marked improvement in insulin and glucose parameters, resulting from an improvement of whole-body insulin sensitivity. Adipose tissue is the major mediator of PPARγ action on insulin sensitivity. PPARγ activation in mature adipocytes induces...

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Autores principales: Leonardini, Anna, Laviola, Luigi, Perrini, Sebastio, Natalicchio, Annalisa, Giorgino, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2009
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826877/
https://ncbi.nlm.nih.gov/pubmed/20182551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/818945
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